Dr. Richard Vile

Dr. Richard Vile, a Mayo Clinic immunologist and cancer researcher, explains how CAR-T cell therapy works, including the benefits, risks and realities of treatment.

Read about the research being conducted to improve CAR-T cell therapy and expand its capabilities to treat more conditions.

Richard Vile, Ph.D., is leading research into genetically engineered viruses called oncolytic viruses for cancer treatment at Mayo Clinic.

Researchers used a new immunotherapy technique that combines chimeric antigen receptor-T cell therapy, or CAR-T cell therapy, with a cancer-killing virus to more effectively target and treat solid cancer tumors in mouse models.