BRCA2

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Researchers resolve uncertainty in BRCA2 testing, improving cancer risk assessment and patient care

Findings will help identify patients with breast, ovarian, pancreatic or prostate cancer who may benefit from targeted therapies.

Photo of Chris Swatfager, Cindy Larson, Carrie Patnode and Amy Scheid. Photo is courtesy of Chris Swatfager.
Mayo Clinic’s DNA study reveals BRCA1 mutations in 3 sisters, prompts life-changing decisions

Minnesota sisters discover they have a shared genetic mutation that dramatically increases their risk for breast and ovarian cancer.

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Large-scale exome sequencing project aims to accelerate discoveries, save lives

Mayo Clinic is sequencing the exomes of tens of thousands of people from diverse backgrounds to investigate large-scale patterns of distinctive mutations that fuel disease.

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Identifying inherited gene mutations in pancreatic cancer can lead to targeted therapies, better survival

A new Mayo Clinic study finds 1 in 6 people with pancreatic cancer harbor inherited genetic mutations.

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Dear Mayo Clinic: Genetic abnormalities and cancer risk

Physician assistant Casey Swanson responds to a question about cancer risk and genetic testing for a BRCA2 mutation.